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    Uremia: Kidney Toxicity and Treatment

    Uremia, sometimes referred to as uremic syndrome, is a dangerous condition in which your kidneys are unable to filter a waste product called urea from your blood.

    Urea, a primary component of urine, is normally removed from the body when you pee (urinate). However, when the kidneys are no longer working—referred to as kidney failure—urea can accumulate to toxic levels.

    Uremia is most often due to kidney failure from advanced chronic kidney disease (CKD).

    Common symptoms include nausea, vomiting, weight loss, lower-stomach pain, and fatigue.

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  • Without treatment in the form of dialysis or a kidney transplant, uremia can get progressively worse, leading to seizures, coma, and death.

    This article describes the symptoms and causes of uremia, including how this potentially deadly complication of kidney disease is diagnosed and treated.

    Emergency Uremia Symptoms to Diagnose

    Uremia is a consequence of kidney failure, the end stage of CKD (also known as end-stage renal disease or ESRD). It can also occur with an acute kidney injury if the

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